100% lethal. Time to ban this reaearch. Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2- related Pangolin Coronavirus GX_P2V(short_3UTR) 4th January 2024 https://www.biorxiv.org/content/10.11… https://www.biorxiv.org/content/10.11…
SARS-CoV-2-related pangolin coronavirus GX_P2V can cause 100% mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain infection. This underscores a spillover risk of GX_P2V into humans, and provides a unique model for understanding the pathogenic mechanisms of SARS-CoV-2-related viruses.